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Alzheimer's Disease

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Joav Prives, Ph.D. is Professor of Pharmacological Sciences in the School of Medicine. He directs an active basic research program in molecular neurobiology focusing on the regulation of synapse formation and muscle differentiation. These studies have direct relevance toward understanding the pathogenesis and etiology of Alzheimer’s disease as well as muscular dystrophy and myasthenia gravis. Additional studies are investigating the mechanisms of action of biological toxins that target neuromuscular synapses.

Areas of Expertise: Pharmacology of synapses; biochemical basis of nerve and muscle disease; chemical and biological neurotoxins.

William E. Van Nostrand, Ph.D. is a Professor in the Department of Medicine. He directs an active basic research program in the biochemistry and molecular pathology involved in the cerebral vascular pathology of Alzheimer's disease and a condition known as cerebral amyloid angiopathy. In addition, other efforts in the laboratory focus on the regulation of thrombosis during cerebral vascular injury that occurs during stroke.

Areas of expertise: Cerebral vascular pathology; neuroinflammation; hemorrhagic and ischemic stroke; proteinase inhibition; transgenic mouse models.

© Stony Brook University 2008

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