STONY BROOK, NY, June 12, 2013 – Erich R. Mackow, PhD, Professor of Molecular Genetics and Microbiology at Stony Brook University School of Medicine, has been elected as a Fellow into the American Academy of Microbiology. The Academy is the prestigious leadership group of the American Society for Microbiology (ASM), the world’s oldest and largest life science organization.
According to the ASM, Academy Fellows are eminent leaders in the field of microbiology and are relied on for authoritative advice and information on critical issues in microbiology. Fellows are elected through a highly selective peer review process based on their records of scientific achievement and original contributions that have advanced microbiology. Dr. Mackow and other newly elected fellows nationwide were recognized at the annual ASM General meeting in May.
Dr. Mackow joined Stony Brook’s Department of Molecular Genetics and Microbiology in 1991. His research investigating the molecular mechanisms of viral pathogenesis focuses mostly on cell signaling responses altered by hantavirus or dengue virus, pathogens that cause hemorrhagic disease or acute respiratory distress termed hantavirus pulmonary syndrome. Dr. Mackow and colleagues in his laboratory have uncovered how hantaviruses affect cell signaling and endothelial cell responses in a process that contributes to vascular leakage and edema. Their findings have led them to devise strategies targeting the endothelium as a potential therapeutic approach for reducing vascular leakage and the severity of hemorrhagic and edematous viral diseases.
“Dr. Mackow’s research with hantaviruses and dengue virus have been essential to helping scientists understand why these emerging pathogens are so virulent,” said Jorge Benach, PhD, Distinguished Professor and Chair of the Department of Molecular Genetics and Microbiology, and Director of Stony Brook’s Center for Infectious Diseases, of which Dr. Mackow is an integral faculty member.
“Hemorrhagic disease caused by dengue and hantaviruses is a serious problem worldwide, and we hope our continued work at Stony Brook leads to therapeutic approaches for reducing the lethality of these diseases and the development of attenuated viruses for vaccine development,” said Dr. Mackow, the keynote speaker at the 2013 International Congress of HFRS, HPS and Hantaviruses in June.
Dr. Mackow and colleagues are currently investigating diseases caused by these viruses and potential treatments by way of several research projects supported by National Institutes of Health (NIH). These include Dengue Virus Induction of Endothelial Cell Responses, ANDV Induced Responses of Hypoxic Endothelial Cells, Biphasic Innate Immunity of Dengue Infected Endothelial Cells and Therapeutic Approaches to Hantavirus Infection.
Dr. Mackow is the editor of the Journal of Virology. He is also the author of nearly 100 peer-reviewed journal articles in virology and microbiology. Dr. Mackow is a member of the American Society for Microbiology, the American Association for the Advancement of Science, the American Society for Virology, and the American Society for Biochemistry and Molecular Biology.
Before coming to Stony Brook, Dr. Mackow was the Senior Research Scientist in the Department of Microbiology and Immunology at Stanford University and the PAVA Medical Center in Palo Alto, Calif. He did his Postdoctoral training at the NIH Laboratory of Infectious Diseases, NIAID in Bethesda, Md. He received his PhD from Temple University in Philadelphia, Pa.